Artificial maturation of the eggs in the laboratory is a safe and effective method of assisted reproduction, where immature eggs are recovered from the ovaries without having been induced by the ovaries. This process restricts the taking of medications, such as gonadotropins, which are expensive, have potential side effects and hide dangers such as ovarian hyperstimulation syndrome.
Natural cycle and artificial ovulation is an alternative method of IVF, especially for patients with polycystic ovary (PCO) or with a high risk of ovarian hyperstimulation syndrome, whether or not combined with a small ovarian condition. In addition to clinical indication, natural cycle and artificial ovulation and egg maturation can be considered as a social and economical alternative to classical IVF, since with the exclusion of drugs there is a significant reduction in treatment costs.
NATURAL CYCLE OR STIMULATED IVF CYCLE?
The major advantage of the natural cycle monitoring is that no medication are required (unless during observation there is a problem), there is limited time required for the couple and the cost is reduced. The downside of the NC is the possibility of anovulation or early rupture of the follicle. This might occur especially in patients with Polycystic Ovarian Syndrome.
DISADVANTAGES OF THE PROGRAM
The major disadvantage of TSI is the inability to monitor fertilization since it takes places following ovulation in the fallopian tubes. Furthermore, there is no significant increase in the percentage of pregnancy achieved in young couples. Another consideration is the psychological disadvantage that couples experience with TSI. A programmed intercourse is often viewed by couples as “forcing” them to have sexual intercourse (especially the male partners)which can have a negative effect in the procedure.
